179 Early eradication of Pseudomonas aeruginosa (PA) in cystic fibrosis patients (CF): Which is the better treatment?

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Early eradication therapy against Pseudomonas aeruginosa in cystic fibrosis patients.

In cystic fibrosis (CF) patients early antibiotic treatment of lung infection has been shown to lead to Pseudomonas aeruginosa eradication. The present study determined: 1) the time period from eradication to new P. aeruginosa acquisition; 2) P. aeruginosa re-growth and new acquisition; and 3) the impact of eradication therapy on lung function, antimicrobial resistance, emergence of other patho...

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Eradication of Pseudomonas aeruginosa in cystic fibrosis.

We read with interest the recently published article by TACCETTI et al. [1] in the European Respiratory Journal and the accompanying editorial by JONES [2]. TACETTI et al. [1] report on their experience with early eradication therapy against Pseudomonas aeruginosa (PA) in cystic fibrosis (CF), concluding that this treatment exerts a number of beneficial effects and is also cost-effective. Howev...

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Antibiotic Susceptibility of Pseudomonas Aeruginosa Isolated from Cystic Fibrosis Patients

Abstract Background and Objective: Cystic fibrosis (CF) is an autosomal recessive genetic disease and Pseudomonas aeruginosa is one of the most common bacteria colonized in CF patients. Growing resistance of this bacterium to antibiotics now a day is a challenge of controlling infection in CF patient. In this study colonization of CF patients with Pseudomonas aeruginosa and antibiotic suscep...

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Eradication of Pseudomonas aeruginosa in adults with cystic fibrosis

BACKGROUND Eradication of new infection of Pseudomonas aeruginosa is an important intervention in managing cystic fibrosis (CF). Previous trials, studying predominantly under 18-year-olds, indicate that antibiotic eradication therapy (AET) has success rates of 62.8-93.0%. In this retrospective cohort study, we report the outcomes of AET in an adult population. METHODS Adults with a confirmed ...

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Eradication Therapy against Pseudomonas aeruginosa in Non-Cystic Fibrosis Bronchiectasis.

BACKGROUND No prospective study has assessed eradication treatment of early Pseudomonas aeruginosa colonisation in bronchiectasis not due to cystic fibrosis (CF). OBJECTIVES To evaluate the efficacy of 3 months of nebulised tobramycin after a short course of intravenous antibiotics in the eradication of P. aeruginosa and its clinical consequences in non- CF bronchiectasis following initial P....

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ژورنال

عنوان ژورنال: Journal of Cystic Fibrosis

سال: 2013

ISSN: 1569-1993

DOI: 10.1016/s1569-1993(13)60320-3